Multiple Neurochemical and Hormonal Mechanisms of Stress-Induced Analgesia
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چکیده
منابع مشابه
Multiple neurochemical and hormonal mechanisms of stress-induced analgesia.
The principal theme of our work on the phenomenon of stress-induced analgesia has been that multiple neurochemically and neurohormonally discrete paininhibitory systems exist and that these systems can be selectively activated by a single stressor, inescapable footshock. Some of these stress-activated endogenous mechanisms of analgesia involve opioid peptides, others do not. Similarly, some for...
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Orexin is produced exclusively in the lateral hypothalamus, where it is known to be involved in pain modulation through brain stem. Due to the important role of this peptide in functions such as eating, sleeping and awaking, addiction, it attracted the attention of researchers in medical sciences specially neuroscientists. These hypothalamic peptides play a critical role in arousal in s...
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For over 30 years, scientists have been investigating the phenomenon of pain suppression upon exposure to unconditioned or conditioned stressful stimuli, commonly known as stress-induced analgesia. These studies have revealed that individual sensitivity to stress-induced analgesia can vary greatly and that this sensitivity is coupled to many different phenotypes including the degree of opioid s...
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Menthol is one of the most commonly used chemicals in our daily life, not only because of its fresh flavor and cooling feeling but also because of its medical benefit. Previous studies have suggested that menthol produces analgesic action in acute and neuropathic pain through peripheral mechanisms. However, the central actions and mechanisms of menthol remain unclear. Here, we report that menth...
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ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 1986
ISSN: 0077-8923,1749-6632
DOI: 10.1111/j.1749-6632.1986.tb14629.x